The short answer
On a Mac there are three real options. LightBurn itself has a paid macOS build with the broadest device list. MeerK40t is free and open-source and runs on macOS, but it is technical and focused on control. Vextrify runs in the browser on any Mac and as a signed desktop app on Apple Silicon Macs; it drives diode and CO2 lasers over USB and prepares the artwork in the same app. LaserGRBL, the best-known free alternative, is Windows-only and is not an option on a Mac.
- LightBurn → paid macOS build, broadest device list
- MeerK40t → free, open-source, technical
- Vextrify → browser plus Apple Silicon app, prep built in