The short answer
If you are on a Mac, skip LaserGRBL: it is Windows-only. LightBurn has a paid Mac build. Rayforge is free and open source and runs on Apple Silicon and Intel Macs. MeerK40t is free too but in maintenance mode. Vextrify runs natively on Apple Silicon Macs as a desktop app, works in any browser to preview your prepared photo (exporting needs a Studio plan), and is also on Windows — with machine control for GRBL diode and Ruida CO2 lasers, camera-accurate placement, one tab per laser, and photo, vector and relief preparation built in.
- LaserGRBL — Windows-only, will not run on a Mac
- LightBurn — paid macOS build
- Rayforge — free, open source, Apple Silicon and Intel
- Vextrify — native Apple Silicon app plus browser and Windows