The short answer
They automate different things. LightBurn's REST API, new in 2.2, lets other programs on your network talk to the running LightBurn app, for example to follow job progress. Vextrify's API takes the customer photo itself: it prepares it for the chosen material and size online and returns a laser-ready file, so a shop order can turn into a prepared file before anyone opens a laser program.
- LightBurn: talk to the running app on the laser computer
- Vextrify: send a photo, get a prepared PNG back
- Both can sit in one workflow